Figure 1.

CONVIVO system mechanism of action. A laser-beam with a specific wavelength is focused on a point inside the object at a specific Z depth. A fluorescent dye that is in the tissue of interest is excited by the laser light and the fluorescence is collected by the lens system and focused onto the tip of the scanned delivery optical fiber, that acts as a confocal pinhole rejecting light other than that from the set Z depth. Then, the fluorescent light is carried to the confocal processor via the optical fiber through a fiber based optical coupler and into a detector, which synchronously samples the fluorescence providing an electrical representation of the light intensity that is recorded as a digital sample. The digital samples are constructed into an image frame that is sent via a digital interface to the integration computer. The integration computer uses custom host software to deliver the image data to a monitor for display and further analysis.