TABLE 3.
ORs of BPH by quartiles of TG/HDL-C and TG/HDL-C stratified by age, BMI, blood pressure, and FBG.
| Q1 | Q2 |
Q3 |
Q4 |
P-trend1 | P-interaction | |
| OR (95% CI) | OR (95% CI) | OR (95% CI) | ||||
| TG/HDL-C | ||||||
| Agea | 0.001 | |||||
| <35 | 1.00 (Ref) | 1.31 (0.81–2.12) | 1.09 (0.63–1.87) | 1.40 (0.81–2.45) | 0.126 | |
| 35–44 | 1.00 (Ref) | 1.36 (1.04–1.79)* | 1.64 (1.26–2.14)*** | 1.69 (1.28–2.22)*** | <0.001 | |
| 45–54 | 1.00 (Ref) | 1.53 (1.27–1.83)*** | 1.71 (1.42–2.05)*** | 1.88 (1.56–2.25)*** | <0.001 | |
| 55–64 | 1.00 (Ref) | 1.56 (1.26–1.93)*** | 1.71 (1.38–2.11)*** | 2.02 (1.63–2.51)*** | <0.001 | |
| ≥65 | 1.00 (Ref) | 1.64 (1.30–2.08)*** | 1.94 (1.51–2.48)*** | 2.04 (1.55–2.68)*** | <0.001 | |
| BMIb | <0.001 | |||||
| 18.5–23.9 | 1.00 (Ref) | 1.74 (1.48–2.05)*** | 2.14 (1.80–2.55)*** | 2.61 (2.15–3.16)*** | <0.001 | |
| 24–27.9 | 1.00 (Ref) | 1.47 (1.25–1.72)*** | 1.67 (1.43–1.95)*** | 1.90 (1.63–2.22)*** | <0.001 | |
| ≥28 | 1.00 (Ref) | 1.54 (1.06–2.23)* | 1.75 (1.22–2.50)** | 2.01 (1.41–2.85)*** | 0.04 | |
| Blood pressurec | 0.379 | |||||
| Normal | 1.00 (Ref) | 1.7 (1.49–1.94)*** | 1.88 (1.64–2.15)*** | 2.21 (1.92–2.55)*** | <0.001 | |
| Hypertension | 1.00 (Ref) | 1.44 (1.20–1.73)*** | 1.77 (1.48–2.11)*** | 1.90 (1.58–2.28)*** | <0.001 | |
| FBGd | 0.013 | |||||
| <6.1 | 1.00 (Ref) | 1.65 (1.47–1.86)* | 1.89 (1.67–2.12)*** | 2.09 (1.85–2.37)*** | <0.001 | |
| ≥6.1 | 1.00 (Ref) | 1.42 (1.09–1.85)** | 1.65 (1.28–2.14)*** | 1.97 (1.53–2.54)*** | <0.001 | |
| TC/HDL-C | ||||||
| Agea | <0.001 | |||||
| <35 | 1.00 (Ref) | 0.54 (0.33–0.9)* | 0.73 (0.45–1.2) | 0.7 (0.41–1.2) | 0.755 | |
| 35–44 | 1.00 (Ref) | 1.13 (0.87–1.48) | 1.41 (1.09–1.82)** | 1.3 (1–1.7) | 0.023 | |
| 45–54 | 1.00 (Ref) | 1.19 (1–1.41) | 1.36 (1.15–1.62)*** | 1.54 (1.3–1.83)*** | <0.001 | |
| 55–64 | 1.00 (Ref) | 1.38 (1.12–1.71)** | 1.7 (1.38–2.09)*** | 1.65 (1.34–2.03)*** | <0.001 | |
| ≥65 | 1.00 (Ref) | 1.23 (0.98–1.55) | 1.45 (1.15–1.84)** | 1.52 (1.19–1.95)*** | <0.001 | |
| BMIb | <0.001 | |||||
| 18.5–23.9 | 1.00 (Ref) | 1.48 (1.26–1.75)*** | 1.69 (1.42–2.02)*** | 2.24 (1.86–2.69)*** | <0.001 | |
| 24–27.9 | 1.00 (Ref) | 1.12 (0.96–1.3) | 1.46 (1.26–1.69)*** | 1.45 (1.26–1.68)*** | <0.001 | |
| ≥28 | 1.00 (Ref) | 1.17 (0.85–1.6) | 1.39 (1.03–1.87)** | 1.45 (1.09–1.93)** | 0.594 | |
| Blood pressurec | 0.002 | |||||
| Normal | 1.00 (Ref) | 1.26 (1.11–1.44)*** | 1.48 (1.3–1.68)*** | 1.56 (1.36–1.78)*** | <0.001 | |
| Hypertension | 1.00 (Ref) | 1.29 (1.08–1.54)** | 1.69 (1.42–2)*** | 1.78 (1.5–2.12)*** | <0.001 | |
| FBGd | 0.002 | |||||
| <6.1 | 1.00 (Ref) | 1.25 (1.11–1.4)*** | 1.6 (1.43–1.8)*** | 1.55 (1.38–1.75)*** | <0.001 | |
| ≥6.1 | 1.00 (Ref) | 1.37 (1.08–1.74)** | 1.37 (1.09–1.73)** | 1.86 (1.49–2.33)*** | 0.005 | |
Model a: WBC, NEUT, FBG, PSA, hypertension, BMI.
Model b: age, WBC, NEUT, FBG, PSA, hypertension.
Model c: age, WBC, NEUT, FBG, PSA, BMI.
Model d: age, WBC, NEUT, PSA, hypertension, BMI.
Ref, reference; OR, odds ratios; CI, confidence interval; TG/HDL-C, triglyceride/high-density lipoprotein cholesterol; TC/HDL-C, cholesterol/high-density lipoprotein cholesterol; WBC, white blood cell; NEUT, neutrophil; FBG fasting blood glucose; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; BMI, body mass index.
*P-value < 0.05.
**P-value < 0.01.
***P-value < 0.001.
1Test for trend based on the variable containing the median value for each quartile.