Table 3.
Predictors of major adverse cardiac event in univariate Cox regression analysis
| Variable | Univariable hazard ratio (CI) |
P-value |
|---|---|---|
| Cardiovascular/clinical risk factors | ||
| Age | 1.05 (1.03–1.07) | <0.001 |
| Male Sex | 0.63 (0.39–1.02) | 0.058 |
| Smoking | 0.55 (0.33–0.92) | 0.022 |
| Hypertension | 2.03 (1.12–3.68) | 0.020 |
| HLP | 0.83 (0.52–1.33) | 0.430 |
| Diabetes | 1.82 (1.14–2.90) | 0.012 |
| BMI | 1.02 (0.97–1.07) | 0.479 |
| Killip class | 2.05 (1.62–2.59) | <0.001 |
| Atrial fibrillation | 2.83 (1.49–5.35) | 0.001 |
| Mitral regurgitation | 2.18 (1.21–3.91) | 0.010 |
| Angiography | ||
| Diseased vessels | 1.50 (1.15–1.97) | 0.004 |
| Culprit lesion | 1.37 (1.10–1.72) | 0.006 |
| TIMI pre | 0.92 (0.76–1.11) | 0.379 |
| TIMI post | 0.82 (0.59–1.15) | 0.244 |
| CMR-derived morphology | ||
| IS | 1.03 (1.01–1.05) | <0.001 |
| MVO | 1.08 (1.02–1.15) | 0.005 |
| AAR | 1.01 (1.00–1.03) | 0.120 |
| MSI | 0.99 (0.98–1.00) | 0.034 |
| LAVI | 1.03 (1.02–1.04) | <0.001 |
| CMR-derived function | ||
| LVEF | 0.94 (0.92–0.96) | <0.001 |
| LV GLS | 1.14 (1.09–1.19) | <0.001 |
| LA Es | 0.90 (0.87–0.94) | <0.001 |
| LAEF | 0.94 (0.93–0.96) | <0.001 |
| LA LAS | 0.85 (0.82–0.88) | <0.001 |
| LA LAS90 | 0.86 (0.83–0.90) | <0.001 |
The table reports univariable Cox regression models to predict a major adverse clinical event during the 12 months follow-up period following acute myocardial infarction. Data are presented as hazard ratios with associated 95% confidence intervals in parentheses. Numbers in bold indicate statistical significance.
CI, confidence interval; HLP, hyperlipoproteinaemia; BMI, body mass index; TIMI, thrombolysis in myocardial infarction grade pre/post PCI; PCI, percutaneous coronary intervention; IS, infarct size; MVO, microvascular obstruction; AAR, area at risk; MSI, myocardial salvage index; LAVI, left-atrial volume index; LVEF, left-ventricular ejection fraction; GLS, global longitudinal strain; Es, reservoir function; LAS, long-axis strain.