Table 4.
Multivariate predictors of major adverse cardiac event
| Variable | 1. Multivariate hazard ratio (CI) |
2. Multivariate hazard ratio (CI) |
3. Multivariate hazard ratio (CI) |
4. multivariate hazard ratio (CI) |
|---|---|---|---|---|
| Cardiovascular/clinical risk factors | ||||
| Age | ||||
| Smoking | ||||
| Hypertension | ||||
| Diabetes | ||||
| Killip class | ||||
| Atrial fibrillation | ||||
| Angiography | ||||
| Diseased vessels | ||||
| Culprit lesion | ||||
| CMR-derived morphology | ||||
| IS | ||||
| MVO | ||||
| MSI | ||||
| LAVI | ||||
| CMR-derived function a | ||||
| LVEF | ||||
| LV GLS | 1.11 (1.02–1.20) P = 0.013 |
1.11 (1.02–1.20) P = 0.011 |
1.10 (1.02–1.20) P = 0.015 |
1.11 (1.03–1.20) P = 0.010 |
| 1 LA Es | ||||
| 2 LAEF | 0.96 (0.92–0.99) P = 0.017 |
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| 3 LA LAS | 0.90 (0.82–0.99) P = 0.036 |
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| 4 LA LAS90 | 0.92 (0.84–1.00) P = 0.050 |
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The table reports multivariable Cox regression models (based on the enter method) to predict a major adverse clinical event during the 12 months follow-up period following acute myocardial infarction. Data are presented as hazard ratios with associated 95% confidence intervals in parentheses. Variables with univariate significance (P < 0.05) were included in multivariable Cox regression models and are presented if they emerged as statistically significant (P < 0.05).
CI, confidence interval; HLP, hyperlipoproteinaemia; BMI, body mass index; IS, infarct size; MVO, microvascular obstruction; MSI, myocardial salvage index; LVEF, left-ventricular ejection fraction; LAVI, left-atrial volume index; GLS, global longitudinal strain; Es, reservoir function; LAS, long-axis strain.
LA Es, LAEF, and LAS/LAS90 were considered in separate multivariate models due to their high correlation (Models 1–4).