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Potential effect modifier with change in τ 2 nd statistical significance for each outcome
| Change in τ 2 | p Value | |
|---|---|---|
| 24 h/day 1 dyspnea relief | ||
| Detsky quality score | −0.02 | .984 |
| Sample size | −0.42 | .706 |
| Men | −1.14 | .335 |
| 48 h dyspnea relief | ||
| Detsky quality score | 0.65 | .632 |
| Sample size | −0.41 | .750 |
| Men | −0.73 | .600 |
| Worsening renal function | ||
| Detsky quality score | −0.70 | .532 |
| Sample size | 0.07 | .949 |
| Men | −0.16 | .880 |
