Table 2.

Patients’ ECMO management and in-ICU complications according to their pregnancy status on ECMO

	All (N = 24)	Ongoing pregnancy on ECMO (N = 11)	Delivery before ECMO (N = 13)	p
Type of ECMO support
Venovenous ECMO	22 (92)	10 (91)	12 (92)	0.90
Venoarterial ECMO	2 (8)	1 (9)	1 (8)	0.90
Switch from VV to VA	1 (4)	1 (9)	0 (0)	0.27
Switch from VV to V-AV	3 (13)	0 (0)	3 (23)	0.09
Switch from VA to VV	1 (4)	0 (0)	1 (8)	0.35
ECMO-related complications
Clogged circuit/membrane requiring a change	1 (4)	1 (9)	0 (0)	0.26
At least one circuit change	10 (42)	2 (18)	8 (62)	0.03
Major bleeding
Cannula bleeding	12 (50)	5 (45)	7 (54)	0.66
Obstetrical bleeding*	8 (33)	2 (18)	6 (46)	0.05
Number of RBC transfusions	7 (0–50)	7 (0–50)	7 (2–23)	0.11
Stroke	2 (8)	1 (9)	1 (8)	0.90
Pneumothorax on ECMO	8 (33)	2 (18)	6 (46)	0.14
Acute kidney injury
KDIGO ≥ 2	9 (38)	3 (27)	6 (46)	0.34
Renal replacement therapy	9 (38)	2 (18)	6 (46)	0.14
≥ 1 antibiotic-treated VAP	14 (58)	4 (36)	10 (77)	0.04
≥ 1 antibiotic-treated bacteremia episode(s)	8 (33)	0 (0)	8 (62)	< 0.01
Tracheostomy	10 (42)	3 (27)	7 (54)	0.19
Tidal volume on ECMO Day 1, ml/kg PBW	3.2 (1.0–7.4)	3.1 (1.0–6.3)	3.2 (1.7–4.0)	0.93
On ECMO
Neuromuscular blockade	21 (88)	10 (91)	11 (85)	0.64
Prone positioning	8 (33)	3 (27)	5 (38)	0.56
Inhaled nitric oxide	3 (13)	1 (9)	2 (15)	0.64
Hypothermia	1 (4)	1 (9)	0 (0)	0.26
Beta-blockers	2 (8)	1 (9)	1 (8)	0.90
Antenatal corticosteroid therapy	14 (58)	7 (63)	7 (54)	0.68

Data are expressed as n (%) or median (range)

ECMO extracorporeal membrane oxygenation; ICU intensive care unit; VV venovenous; VA venoarterial; V-AV veno-arteriovenous; RBC red blood cells; KDIGO Kidney Disease Improving Global Outcomes; PBW Predicted Body Weight

*Uterine bleedings or abdominal parietal hematoma or hemoperitoneum