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Predictive and prognostic significance of PD-L1 and TMB in PLELC. (A) TMB levels in ICI-treated PLELC-DCB patients versus NDCB patients. (B) Proportion of different PD-L1 expression in DCB patients versus NDCB patients. (C, D) PFS and OS of patients with PD-L1 <1% versus ≥1% in PLELC patients treated with ICI monotherapy. (E, F) PFS and OS of patients with PD-L1 <1% versus ≥1% in PLELC patients treated with ICI combination therapy.
