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. 2022 Sep 19;68(8):1115–1119. doi: 10.1590/1806-9282.20211383

Table 2. Platelet therapy growth factor functions.

Platelet-derived growth factor (PDGFaa, PDGFbb, PDGFab) Triggers the activities of neutrophils, fibroblasts, and macrophages
Chemoattractant/cell proliferator
Stimulates mesenchymal cell lineages
Transforming growth factor (TGF-β1, TGF-β2, TGF-β3) Promotes cellular differentiation and replication
Stimulates matrix and collagen synthesis
Stimulates fibroblast activity and collagen production
Vascular endothelial growth factor (VEGF) … Angiogenesis
… Stimulates synthesis of basal lamina
Fibroblastic growth factor (FGF) Angiogenesis
Fibroblast production
Epithelial cell growth factor (ECGF) Stimulates epithelial cell replication
Insulin-like growth factor (IGF-1) Promotes cellular growth and proliferation