Table 1. Cross-activity of 1–4 against BTK and JAK3.
| IC50 (nM) |
||
|---|---|---|
| Compound | BTK | JAK3 |
| 1 | 16.11 ± 0.01 | 698.80 ± 129.26 |
| 2 | 98.28 ± 0.64 | 6.16 ± 2.06 |
| 3 | 1898.50 ± 94.05 | 8.97 ± 3.04 |
| 4 | 637.75 ± 84.64 | 32.59 ± 1.33 |
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