Table 3.

The 11 candidate SNPs showing significant frequencies differences between the different evaluated populations

Groups	Types of SNPs	Type of amino acid change	Variants	Genes	A= Frequency in the studied Lebanese cohort	B= Frequency in the local Lebanese database	C= Frequency in gnomAD	Difference A vs. B	Difference A vs. C	99.9999999% CI of A
Group 1	3 Prime UTR Variant	Pyrimidine to pyrimidine	rs1707	HLA-G	0.529411765	0.20127119	0.8574	Yes	Yes	[0.24714813–0.798697334]
	3 Prime UTR Variant	Pyrimidine to purine	rs1063320	HLA-G	0.215686275	0.0286017	0.516	Yes	Yes	[0.04591686–0.509931283]
Group 2	3 Prime UTR Variant	Pyrimidine to pyrimidine	rs9299	HOXB-AS3	0.12745098	0.19597458	0.531	No	Yes	[0.01361905–0.402416044]
	3 Prime UTR Variant	Pyrimidine to pyrimidine	rs696	NFKBIA	0.019607843	0.14830509	0.4574	No	Yes	[3.04E-06-0.227119758]
	Non-Coding Transcript Variant	Purine to purine	rs1061217	SLAMF1	0.509803922	0.28495763	0.00003191	No	Yes	[0.23147854–0.783803061]
	Intron Variant	Pyrimidine to pyrimidine	rs1799794	XRCC3	0.009803922	0.00423729	0.2219	No	Yes	[7.4861E-09-0.203334752]
	Intron Variant	Pyrimidine to pyrimidine	rs1799796	KLC1; XRCC3	0.205882353	0.194915254	0	No	Yes	[0.04162045–0.49880505]
	Intron Variant	Purine to purine	rs1805335	RAD23B	0.607843137	0.44809322	0.000004051	No	Yes	[0.313778362–0.854357768]
Group 3	3 Prime UTR Variant	Purine to pyrimidine	rs1710	HLA-G	0.431372549	0.150423729	0.5169	Yes	No	[0.172681469–0.720337798]
	Upstream gene_variant	Not applicable	rs3213239	PINLYP	0.411764706	0.13559322	0.6146	Yes	No	[0.158961335–0.703483575]
	Intron Variant	Purine to pyrimidine	rs1801320	RAD51	0.019607843	0	0.1266	Yes	No	[3.03998E-06-0.227119758]

CI: confidence interval p-value :10^–10. In “Difference A vs. B” and “Difference A vs. C” columns, “Yes” designates a statistically significant difference, while “No” indicates that there is no statistically significant difference