Table 2.
Triangular motifs for depression severity and taxonomic and functional abundances. Listed are all triangular motifs within the joint network, formed by taxonomic-metabolic, taxonomic-psychopathological and metabolic-psychopathological associations. Related associations are alternately highlighted in grey or white
| Association | Log10BF(10) | Rho | |
|---|---|---|---|
| Depression | |||
| Bacteroidetes: Odoribacter | Carbohydrate metabolism: pectin degradationa | 2.026 | 0.455 |
| Bacteroidetes: Odoribacter | Depression: HADS | 1.956 | − 0.457 |
| Carbohydrate metabolism: pectin degradationa | Depression: HADS | 0.804 | − 0.343 |
| Bacteroidetes: Odoribacter | Carbohydrate metabolism: PRPP biosynthesisb | 1.291 | − 0.390 |
| Bacteroidetes: Odoribacter | Depression: HADS | 1.956 | − 0.457 |
| Carbohydrate metabolism: PRPP biosynthesisb | Depression: HADS | 0.655 | 0.324 |
| Bacteroidetes: Odoribacter | Glycan metabolism: dermatan sulfate degradationc | 2.611 | 0.498 |
| Bacteroidetes: Odoribacter | Depression: HADS | 1.956 | − 0.457 |
| Glycan metabolism: dermatan sulfate degradationc | Depression: HADS | 0.530 | − 0.307 |
| Bacteroidetes: Alistipes | Glycan metabolism: dermatan sulfate degradationc | 1.644 | 0.423 |
| Bacteroidetes: Alistipes | Depression: HADS | 0.997 | − 0.365 |
| Glycan metabolism: dermatan sulfate degradationc | Depression: HADS | 0.530 | − 0.307 |
| Firmicutes: Anaerotruncus | Glycan metabolism: dermatan sulfate degradationc | 1.098 | 0.370 |
| Firmicutes: Anaerotruncus | Depression: HADS | 0.530 | − 0.307 |
| Glycan metabolism: dermatan sulfate degradationc | Depression: HADS | 0.666 | − 0.326 |
| Fatigue | |||
| Firmicutes: Intestinimonas | Amino acid metabolism: methionine biosynthesisd | 0.509 | − 0.300 |
| Firmicutes: Intestinimonas | Fatigue: WEIMuS | 0.972 | − 0.363 |
| Amino acid metabolism: methionine biosynthesisd | Fatigue: WEIMuS | 0.959 | 0.361 |
| Firmicutes: Eubacterium | Carbohydrate metabolism: pentose phosphate pathwaye | 1.082 | − 0.369 |
| Firmicutes: Eubacterium | Fatigue: WEIMuS | 0.655 | − 0.324 |
| Carbohydrate metabolism: pentose phosphate pathwaye | Fatigue: WEIMuS | 0.715 | 0.332 |
| Firmicutes: Anaerotruncus | Carbohydrate metabolism: pentose phosphate pathwaye | 0.554 | − 0.306 |
| Firmicutes: Anaerotruncus | Fatigue: WEIMuS | 0.662 | − 0.325 |
| Carbohydrate metabolism: pentose phosphate pathwaye | Fatigue: WEIMuS | 0.715 | 0.332 |
| Firmicutes: Clostridiales genus incertae sedis | Carbohydrate metabolism: pentose phosphate pathwaye | 2.900 | − 0.517 |
| Firmicutes: Clostridiales genus incertae sedis | Fatigue: WEIMuS | 0.660 | − 0.325 |
| Carbohydrate metabolism: pentose phosphate pathwaye | Fatigue: WEIMuS | 0.715 | 0.332 |
aKEGG—path: map00040—map01100
bKEGG—path: map00030—map00230—map01200—map01230—map01100
cKEGG—path: map00531—map01100
dKEGG—path: map00270—map01230—map01100
eKEGG—path: map00030—map01200—map01230—map01100—map01120