Table 2.

Unweighted and propensity score weighted baseline characteristics.

	Unweighted, N = 238			Weighted, N = 238
Variables, mean ± standard deviation	Normal ECG N = 103	Abnormal ECG N = 135	KS p-value	Normal ECG N = 103	Abnormal ECG N = 135	KS p-value
Age (years)	58 ± 15	65 ± 16	0.0050	59 ± 15	63 ± 16	0.22
Male sex (binary)	0.74 ± 0.44	0.73 ± 0.44	0.94	0.73 ± 0.45	0.75 ± 0.45	0.68
BMI	28 ± 6.6	27 ± 5.1	0.45	28 ± 6.4	27 ± 5.1	0.69
Comorbidities (binary, yes)
Diabetes	0.17 ± 0.37	0.27 ± 0.45	0.048	0.16 ± 0.37	0.26 ± 0.44	0.072
Hypertension	0.36 ± 0.48	0.53 ± 0.50	0.011	0.37 ± 0.48	0.50 ± 0.50	0.061
Hyperlipidemia	0.13 ± 0.33	0.19 ± 0.39	0.17	0.13 ± 0.34	0.13 ± 0.39	0.31
IHD	0.068 ± 0.25	0.16 ± 0.36	0.040	0.079 ± 0.27	0.14 ± 0.35	0.16
Prior AMI	0.058 ± 0.23	0.11 ± 0.31	0.16	0.067 ± 0.25	0.10 ± 0.31	0.35
Prior stroke	0.087 ± 0.28	0.17 ± 0.38	0.065	0.10 ± 0.30	0.15 ± 0.35	0.30
Prior VTE	0.039 ± 0.19	0.059 ± 0.24	0.48	0.038 ± 0.19	0.061 ± 0.24	0.43
HFrEF	0.019 ± 0.14	0.052 ± 0.22	0.20	0.024 ± 0.15	0.047 ± 0.21	0.37
HFpEF	0	0.037 ± 0.19	0.048	0	0.032 ± 0.18	0.036
History of AF	0.068 ± 0.25	0.19 ± 0.39	0.0060	0.077 ± 0.27	0.17 ± 0.37	0.048
Peripheral artery disease	0	0.022 ± 0.15	0.13	0	0.022 ± 0.15	0.10
COPD	0.049 ± 0.22	0.059 ± 0.24	0.72	0.051 ± 0.22	0.056 ± 0.23	0.85
Astma	0.068 ± 0.25	0.052 ± 0.22	0.60	0.062 ± 0.24	0.055 ± 0.23	0.80
CKD	0.01 ± 0.10	0.089 ± 0.29	0.0080	0.011 ± 0.10	0.073 ± 0.26	0.030
Active cancera	0.039 ± 0.19	0.059 ± 0.24	0.48	0.047 ± 0.21	0.058 ± 0.23	0.72
Any dementiab	0.019 ± 0.14	0.037 ± 0.19	0.43	0.024 ± 0.15	0.037 ± 0.19	0.62
Smokingc	0.53 ± 0.50	0.56 ± 0.50	0.88	0.54 ± 0.50	0.55 ± 0.50	0.99
Medication at admission (yes)
Beta-blockers	0.18 ± 0.38	0.33 ± 0.47	0.0090	0.20 ± 0.40	0.30 ± 0.46	0.084
Anti-arrhythmic agentd	0	0.015 ± 0.12	0.22	0	0.011 ± 0.10	0.19
Digoxin	0	0.022 ± 0.15	0.13	0	0.021 ± 0.14	0.11
Aspirin	0.068 ± 0.25	0.15 ± 0.36	0.055	0.077 ± 0.27	0.14 ± 0.35	0.14
Warfarin	0.01 ± 0.098	0.037 ± 0.19	0.19	0.0080 ± 0.088	0.033 ± 0.18	0.15
DOAC	0.068 ± 0.25	0.15 ± 0.36	0.055	0.079 ± 0.27	0.13 ± 0.34	0.21
ACE inhibitor	0.17 ± 0.37	0.24 ± 0.43	0.14	0.17 ± 0.38	0.23 ± 0.42	0.26
ARB	0.12 ± 0.32	0.13 ± 0.34	0.70	0.12 ± 0.33	0.13 ± 0.33	0.91
Calcium antagonist	0.17 ± 0.37	0.20 ± 0.40	0.49	0.17 ± 0.38	0.19 ± 0.40	0.71
Statins	0.21 ± 0.41	0.33 ± 0.47	0.057	0.23 ± 0.42	0.30 ± 0.46	0.24
P2Y12 inhibitor	0.019 ± 0.14	0.096 ± 0.30	0.017	0.022 ± 0.15	0.083 ± 0.28	0.058
MRA	0.029 ± 0.17	0.022 ± 0.15	0.74	0.033 ± 0.18	0.021 ± 0.14	0.57
Diuretics	0.058 ± 0.23	0.17 ± 0.38	0.010	0.068 ± 0.25	0.15 ± 0.36	0.061
Oral antidiabetics	0.15 ± 0.35	0.22 ± 0.41	0.18	0.14 ± 0.35	0.20 ± 0.40	0.22
Oral cortisone	0.049 ± 0.22	0.059 ± 0.24	0.72	0.056 ± 0.23	0.052 ± 0.22	0.90
Symptoms and signs at admission
Systolic BP (mmHg)	126 ± 21	128 ± 22	0.69	126 ± 21	127 ± 22	0.81
Diastolic BP (mmHg)	77 ± 13	75 ± 13	0.24	77 ± 13	76 ± 13	0.58
Heart rate (bpm)	95 ± 18	100 ± 23	0.13	95 ± 18	99 ± 22	0.45
Respiratory rate (brpm)	27 ± 8.4	26 ± 8.0	0.96	27 ± 8.2	26 ± 8.0	0.96
Saturation no oxygen %	88 ± 8.2	88 ± 12	0.37	88 ± 8.6	88 ± 11	0.87
Oxygen at admission % (n/N)e	0.76 ± 0.43	0.67 ± 0.47	0.13	0.74 ± 0.44	0.68 ± 0.47	0.30
Ct value (cycles)	28 ± 5.7	27 ± 5.9	0.35	27 ± 5.7	27 ± 5.6	0.65
Fever % (n/N)f	0.64 ± 0.48	0.58 ± 0.49	0.33	0.63 ± 0.48	0.58 ± 0.49	0.43
Cough	0.82 ± 0.39	0.77 ± 0.42	0.40	0.80 ± 0.40	0.78 ± 0.42	0.66
Dyspnea	0.70 ± 0.46	0.68 ± 0.47	0.77	0.69 ± 0.46	0.68 ± 0.47	0.81
Sore throat	0.16 ± 0.36	0.13 ± 0.33	0.52	0.15 ± 0.35	0.14 ± 0.34	0.83
Nasal congestion	0.019 ± 0.14	0.037 ± 0.19	0.43	0.022 ± 0.15	0.031 ± 0.17	0.688
Loss of smell	0.12 ± 0.32	0.044 ± 0.21	0.039	0.10 ± 0.30	0.048 ± 0.21	0.11
Loss of taste	0.097 ± 0.30	0.052 ± 0.22	0.18	0.083 ± 0.28	0.059 ± 0.24	0.47
Headache	0.12 ± 0.32	0.089 ± 0.29	0.49	0.11 ± 0.32	0.092 ± 0.29	0.58
Chest pain	0.16 ± 0.36	0.074 ± 0.26	0.048	0.14 ± 0.35	0.080 ± 0.27	0.13
Abdominal pain	0.039 ± 0.19	0.030 ± 0.17	0.70	0.040 ± 0.20	0.029 ± 0.17	0.65
Vomiting	0.087 ± 0.28	0.074 ± 0.26	0.71	0.087 ± 0.28	0.072 ± 0.26	0.68
Diarrhea	0.18 ± 0.38	0.11 ± 0.31	0.16	0.17 ± 0.37	0.12 ± 0.32	0.28
Disorientationg	0.058 ± 0.23	0.13 ± 0.34	0.058	0.077 ± 0.27	0.12 ± 0.32	0.33

ECG = electrocardiogram; KS = Kolmogorov-Smirnov; BMI = body mass index; IHD = ischemic heart disease; AMI = acute myocardial infarction; VTE = venous thromboembolism: HFrEF = heart failure reduced ejection fraction; HFpEF = heart failure preserved ejection fraction; AF = atrial fibrillation; COPD = chronic obstructive pulmonary disease; CKD = chronic kidney disease; DOAC = Direct-acting oral anticoagulant; ACE = angiotensin-converting enzyme; ARB = angiotensin receptor blocker; MRA = mineralocorticoid receptor antagonist; BP = blood pressure; bpm = beats per minute; brpm = breaths per minute; Ct value = cycle threshold value.

^aAny active cancer.

^bAny dementia diagnosis prior to admission; ^ccurrent or ex-smoker; ^dNon beta-blocker anti-arrhythmic medication.

^eTreated with oxygen or not treated with oxygen at admission.

^fBody temperature ≥ 38 degrees Celsius.

^gNew disorientation aggravated previous disorientation.