Table 2:
Multivariable linear mixed-effects modeling of CBF based on clinical, demographic, and study factorsa
| Mod_Baseline | Mod_HCP | Mod_HCPCMS | |
|---|---|---|---|
| (Intercept) | 43.3 (3.86)b | 48.4 (4.06)b | 50.1 (4.70)b |
| Postop time point | 6.21 (2.00)c | 3.01 (2.08) | 1.55 (2.20) |
| Follow-up time point | 14.8 (2.07)b | 10.5 (2.15)b | 7.74 (2.31)b |
| Age | −0.686 (0.45) | −1.17 (0.53)d | −1.34 (0.59)d |
| Thalamus | −5.55 (1.60)b | −5.59 (1.51)b | −5.60 (1.45)b |
| Cerebellum | −10.0 (1.59)b | −10.0 (1.50)b | –10.0 (1.44)b |
| Unsedated (vs GA) | – | 3.57 (3.79) | 5.73 (3.93) |
| Hydrocephalus | – | −19.4 (6.04)c | −20.5 (6.27)c |
| Postop time point + HCP | – | 21.5 (5.17)b | 24.0 (5.13)b |
| Follow-up time point + HCP | – | 26.0 (5.22)b | 27.2 (5.18)b |
| CMS | – | – | −10.9 (6.46)e |
| Postop time point + CMS | – | – | 8.74 (5.26)e |
| Follow-up time point + CMS | – | – | 15.6 (5.28)c |
| AIC | 1841.5 | 1824.7 | 1821.8 |
| Marginal R2 | 0.224 | 0.290 | 0.295 |
| Conditional R2 | 0.607 | 0.650 | 0.692 |
Note:—– indicates not included in model; GA, general anesthesia; Post-op, postoperative.
a
Values are coefficients (standard error).
b
P < .001.
c
P < .01.
d
P < .05.
e
P < .1.