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. 2022 Oct 3;13:1006101. doi: 10.3389/fendo.2022.1006101

Figure 2.

Figure 2

The structure of the androgen receptor gene and protein. The AR gene is situated on position q11-12 of chromosome X and contains 8 exons. The protein reference sequence NM_000044.3 is comprised of 920 amino acids and is composed of different domains which are depicted. In addition, posttranslational modifications known to influence AR function are shown. AR, androgen receptor; bp, base pair; NTD, N-terminal domain; DBD, DNA binding domain; LBD, ligand binding domain; AF, activation function; TAU, transcription activation unit; NLS, nuclear localisation signal; NES, nuclear export signal.