TABLE 4.
A summary of all the significant group comparisons of shape thickness between OCD patients and healthy controls (p < 0.05, corrected for multiple comparisons with FDR Searchlight)
| Shape thickness effect size (Cohen's d) and percentage change in the structure | |||||||
|---|---|---|---|---|---|---|---|
| Group comparison | Amygdala | Hippocampus | Putamen | Caudate nucleus | Nucleus accumbens | Thalamus | Pallidum |
| OCDdep (n = 101) vs. controls (n = 368) | Ns | LH: d = −0.135 (5.4%) | RH: d = 0.167 (6.5%) | LH: d = −0.132 (2.8%) | Ns | Ns | RH: d = 0.159 (7.8%) |
| OCDanx (n = 190) vs. controls (n = 368) | Ns | LH: d = −0.111 (2.4%) | RH: d = 0.205 (7.8%) | LH: d = −0.139 (5.6%) | Ns | Ns | RH: d = 0.202 (4.3%) |
| OCDmed (n = 176) vs. controls (n = 368) | Ns | RH: d = −0.146 (4.6%) | LH: d = −0.115 (7.1%) | RH: d = 0.175 (4.4%) | Ns | RH: d = −0.126 (6.4%) | RH: d = 0.177 (5.9%) |
| LH: d = −0.161 (5.8%) | |||||||
Abbreviations: Ns: not significant; OCD: obsessive‐compulsive disorder; OCDanx: OCD patients with comorbid anxiety disorder; OCDdep: OCD patients with comorbid major depression; OCDmed: OCD patients on medication.