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. 2022 Oct 3;13:993788. doi: 10.3389/fimmu.2022.993788

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Copyright © 2022 Huang, Yan, Dong, Jiao, Wang, Li and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MST1-p38MAPK regulated the function of macrophages. (A, B) Representative western blot and relative protein expression of MST1 and p38-MAPK after transfecting cells with siRNA-MST1. (C) The mRNA level of MST1 and p38-MAPK after transfecting cells with siRNA-MST1 by RT-PCR. (D, E) Representative flow cytometry to evaluate the polarization state when the expression of MST1 was decreased. (F) Cell viability after transfection. (G) The IL-10 concentration of the culture supernatant after transfection of siRNA-MST1 in THP-1. **P < 0.01, ***P < 0.001, ****P < 0.0001, ns means not statistically significant. Values represent the mean ± standard error.