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. Author manuscript; available in PMC: 2022 Oct 17.
Published in final edited form as: IEEE Trans Comput Imaging. 2022 May 12;8:462–478. doi: 10.1109/tci.2022.3174801

Fig. 5.

Fig. 5.

Comparison of PCA and DM embeddings of the 400 images of the “mouth-wing” toy model in SS2 from a given PD. The anticipated 20 × 20 parabolic surface is obtained by both techniques. Of note, the points in the PCA embedding have a slightly-less uniform distribution than those in the DM embedding, suggesting that DM better approximates intrinsic relationships in the data. Overall, these results closely match those obtained from application of PCA and DM on the Hsp90 SS2 synthetic continuum.