Table 2.
Correlation between miR-92a and clinical characteristics of patients with non-small cell lung cancer. According to the expression level of miR-92a in tumor tissues. We divided 100 patients with non-small cell lung cancer into miR-92a high expression group (n = 50) and miR-92a low expression group (n = 50). The clinicopathological parameters of 100 patients with non-small cell lung cancer were measured. The clinicopathological parameters was expressed as a percentage.
| Clinicopathological parameters | N | Expression of miR-92a | χ2 | P | |
|---|---|---|---|---|---|
| High expression (n = 50) | Low expression (n = 50) | ||||
| Age (yr) | |||||
| <60 | 34 | 16 (32%) | 18 (36%) | 0.000 | 1.000 |
| ≥60 | 66 | 34 (68%) | 32 (64%) | ||
| Gender | |||||
| Male | 54 | 28 (56%) | 26 (52%) | 0.482 | .628 |
| Female | 46 | 22 (44%) | 24 (48%) | ||
| Local invasion | |||||
| T1/T2 | 49 | 12 (24%) | 37 (74%) | 5.182 | .039 |
| T3/T4 | 51 | 38 (76%) | 13 (26%) | ||
| Organization type | |||||
| Squamous cell carcinoma | 47 | 23 (46%) | 24 (48%) | 0.237 | .769 |
| Adenocarcinoma | 53 | 27 (54%) | 26 (52%) | ||
| Tumor size | |||||
| ≥3 cm | 51 | 26 (52%) | 25 (50%) | 0.254 | .712 |
| <3 cm | 49 | 24 (48%) | 25 (50%) | ||
| Lymph node metastasis | |||||
| No | 51 | 16 (32%) | 35 (70%) | 4.892 | .042 |
| Yes | 49 | 34 (68%) | 15 (30%) | ||
| Distant metastasis | |||||
| M0 | 39 | 21 (42%) | 31 (62%) | 2.2815 | .084 |
| M1 | 71 | 29 (58%) | 19 (38%) | ||
| Clinical staging | |||||
| Stage I/II | 32 | 13 (26%) | 32 (64%) | 6.748 | .028 |
| Stage III/IV | 68 | 37 (74%) | 18 (36%) | ||