Table 1. Baseline characteristics of the study population.
| Variables | Total (n = 114) | Healthy control, (n = 38) | Atrophic gastritis (n = 40) | Gastric cancer (n = 36) | р value |
|---|---|---|---|---|---|
| Age, mean (SD) * | 59.98 (10.88) | 59.87 (11.62) | 58.73 (10.79) | 61.50 (10.26) | - |
| Gender, male (%) * | 60 (52.6) | 20 (52.6) | 21 (52.5) | 19 (52.8) | - |
| Family history of gastric cancer (%) | 24 (21.1) | 7 (18.4) | 4 (10.0) | 13 (36.1) | 0.018 |
| Previous history of gastrointestinal diseases (%) | 35 (30.7) | 6 (15.8) | 10 (25.0) | 19 (52.8) | 0.002 |
| H. pylori IgG >30EIU (%) | 67 (58.8) | 24 (63.2) | 22 (55.0) | 21 (58.3) | 0.764 |
| PGI ng/ml, median (min, max) | 59.38 (4.23, 223.94) | 74.32 (14.65, 223.94) | 56.52 (4.23, 209.28) | 46.94 (6.52, 212.67) | 0.067 |
| PGII ng/ml, median (min, max) | 13.11 (3.73, 41.77) | 13.32 (6.24, 39.48) | 11.39 (4.20, 40.75) | 16.60 (3.73, 41.77) | 0.084 |
| PGR, median (min, max) | 4.80 (0.58, 13.37) | 5.77 (1.71, 12.87) | 5.03 (0.60,13.73) | 3.76 (0.58, 8.71) | 0.004 |
| G-17 pmol/l, median (min, max) | 12.36 (0.11, 78.69) | 13.99 (0.80, 78.69) | 10.64 (0.96–45.80) | 13.41 (0.11, 77.49) | 0.091 |
*Age and gender were matched between study groups.
PGI, pepsinogen I; PGII, pepsinogen II; PGR, pepsinogen I to pepsinogen II ratio; G-17, gastrin-17.