TABLE 5.
Lysis of IIIB-coated CD4 lymphocytes mediated by PBMC of HIV-infected children in the presence of adult serum
| HIV status of children | Characteristic of
childrenc
|
% Lysis of CD4-IIIB in
the presence of adult serum
|
|||
|---|---|---|---|---|---|
| Age | Stage (CDC classification) | Absolute CD4 cell count/mm3 | HIV seronegativea | HIV seropositiveb | |
| Seropositive | 3 mo | P1-A | 3,000 | 0.6 | 0 |
| 6 mo | P2-C | 950 | 0 | 0 | |
| 7 mo | P1-B | 950 | 1.8 | 1.9 | |
| 1 yr | P1-A | 3,000 | 0 | 0 | |
| 1 yr | P1-A | 5,000 | 4.0 | 12.6 | |
| 1 yr | P2-A | 1,000 | 0 | 0 | |
| 1 yr | P2-A | 1,550 | 1.0 | 8.9 | |
| 1 yr | P2-D1 | 280 | 0 | 6.8 | |
| 1 yr | P2-D1 | 790 | 0 | 20.3 | |
| 2 yr | P2-A | 500 | 0.9 | 0.3 | |
| 2 yr | P2-D1 | 1,200 | 0 | 0 | |
| 2 yr | P2-D1 | 1,000 | 0 | 0 | |
| 4 yr | P2-C | 200 | 0 | 15.5 | |
| 10 yr | P1-B | 185 | 0 | 10.1 | |
| 10 yr | P2-A | 100 | 0 | 13.1 | |
| Seronegative | 15 mo | NA | ND | 0 | 1.3 |
| 2 yr | NA | ND | 0 | 6.9 | |
| 3 yr | NA | ND | 0 | 16.6 | |
| 5 yr | NA | ND | 0 | 10.8 | |
| 5 yr | NA | ND | 0 | 6.5 | |
| 5 yr | NA | ND | 0 | 8.9 | |
| 5 yr | NA | ND | 0 | 7.4 | |
| 8 yr | NA | ND | 0 | 3.7 | |
| 11 yr | NA | ND | 0 | 10.2 | |
a
Sera obtained from HIV-seronegative adults.
b
Sera obtained from HIV-infected asymptomatic adults.
c
NA, not applicable; ND, not determined.