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Grade 4 vessel from case with known ARIA-E during life. Adjacent Aβ, fibrin(ogen), GFAP and CD68 sections are shown. Vessel with no vascular Aβ, evidence of fibrin within the vessel wall and perivascular reactive astrocytes and activated microglia. Aβ inset displays Aβ deposition in a region of this vessel remote from the site of remodelling. Arrowhead and arrow point to examples of a reactive astrocyte and activated microglial cell, respectively.
