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Representative chromatograms of nirmatrelvir and ritonavir in human plasma. Top row: drug free human plasma without internal standard. Middle row: calibration level 1 (LLOQ) containing 10 ng/mL nirmatrelvir and 2 ng/mL ritonavir. Bottom row: patient sample containing 899 ng/mL nirmatrelvir and 131 ng/mL ritonavir.
