Table 5. Associations of serum E2 levels instrumented by rs7173595 in the CYP19A1 gene region with COVID-19 outcomes.
| Sex | Phenotype | beta | SE | OR (95% CI) | p Effect |
|---|---|---|---|---|---|
| Female | Susceptibility | –1.14 | 0.88 | 0.32 (0.06, 1.80) | 0.195 |
| Hospitalization | –1.27 | 1.60 | 0.28 (0.01, 6.46) | 0.426 | |
| Severity | –1.49 | 2.06 | 0.22 (0.00, 12.73) | 0.469 | |
| Male | Susceptibility | –1.00 | 0.77 | 0.37 (0.08, 1.67) | 0.195 |
| Hospitalization | –1.11 | 1.40 | 0.33 (0.02, 5.11) | 0.426 | |
| Severity | –1.31 | 1.80 | 0.27 (0.01, 9.26) | 0.469 |
E2, estradiol; OR, odds ratio; CI, confidence interval.