FIG. 5.

(A) Seroconversion of four ewes after experimental infection with MVV. For each animal, the time of first AGIDT-positive bleeding is indicated between parentheses (days postinfection). For each sample, ELISA as well as AGIDT analysis of the serum was performed. The ELISA result is considered positive when the S/CO is >1. The values at time zero are the means of results for four control bleedings taken during a period of 200 days prior to infection. Bleeding samples of an uninfected control sheep were analyzed in parallel over a period of 303 days (11 bleedings) and the S/CO was always below the cutoff (between 0.21 and 0.78). (B) Vertical transmission of MVV infection in four lambs born to MVV-infected dams. For each lamb, the first AGIDT-positive bleeding (bleeding number) is indicated after the animal identification number. For each sample, ELISA as well as AGIDT analysis was performed. An S/CO of >1 is considered a positive result.