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. 2022 Oct 10;2022:8130132. doi: 10.1155/2022/8130132

Figure 3.

Figure 3

Suppression of NEAT1 in repressing cell proliferation and invasion of CRC. (a) SW620 and HCT-116 cells transfected with NEAT1-1 or NEAT1-2 for validation by qRT-PCR. (b) CCK-8 assay was prepared to detect cell proliferation of CRC. (c) Flow cytometry assay has explored the effect of NEAT1 knockdown in inhibition of cell cycle in SW620 and HCT-116 cells. (d) Flow cytometry assay was performed to discover NEAT1 knockdown in promotion of apoptosis in SW620 and HCT-116 cells. (e) Transwell assay was prepared to detect cell invasive and migration after silencing of NEAT1 expression in SW620 and HCT-116 cells. (f) Cell colony assay was used to verify silencing of NEAT1 expression decreases cell proliferation. P < 0.05, ∗∗p < 0.01, compared with the NC group.