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. 2022 Oct 18;14:3021–3036. doi: 10.2147/CMAR.S382464

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© 2022 Xie et al.

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(A) Gram stain: Gram-negative bacteria appear red when stained. Original magnification 1000×. (B) F. nucleatum was positive by immunohistochemistry, original magnification 1000×. C-P: Immunohistochemical detection. Original magnification 400×. (C) Negative F. nucleatum expression in paracancerous tissue, (D) positive F. nucleatum expression in paracancerous tissue, (E) negative F. nucleatum expression in cancer tissue, (F) positive F. nucleatum expression in cancer tissue, (G) negative MLH-1 expression, (H) positive MLH-1 expression, (I) negative MSH2 expression, (J) positive MSH2 expression, (K) negative PMS2 expression, (L) positive PMS2 expression, (M) negative MSH6 expression, (N) positive MSH6 expression, (O) negative HER-2 expression, (P) positive HER-2 expression.