Table 7.

Receiver Operating Characteristic Curve Analysis of Parameters

Variable	AUC	Std. Error	95% CI	P value	Sensitivity(%)	Specificity (%)
Age	0.711	0.053	0.607–0.815	0.001**	88.2	54.0
TNM stages	0.677	0.057	0.566–0.789	0.004**	73.5	61.9
F. nucleatum	0.591	0.061	0.471–0.711	0.139	50.0	68.3
Sex	0.530	0.062	0.409–0.651	0.626	44.1	61.9
MSI	0.529	0.062	0.407–0.651	0.637	26.5	79.4
CgA	0.506	0.506	0.384–0.582	0.928	5.9	95.2
Syn	0.464	0.061	0.35–0.582	0.555	11.8	81.0
CD31	0.449	0.062	0.327–0.571	0.412	67.6	22.2
D2-40	0.449	0.062	0.327–0.571	0.412	67.6	22.2
HER-2	0.411	0.061	0.292–0.531	0.150	44.1	38.1
Tumor location	0.364	0.058	0.250–0.477	0.027*	23.5	49.2

Notes: AUC indicates the ability of the biomarkers and combined components to analyze prognosis; *p <0.05 and **p<0.01 were considered to be statistically significant.

Abbreviations: AUC area under the curve; Std, standard; 95% CI, 95% confidence interval; F. nucleatum, Fusobacterium nucleatum; HER-2, human epidermal growth factor receptor-2; MSI, microsatellite instability; Syn, synaptophysin; CgA, chromogranin A.