Table 9.
Univariate Analysis of the Impact of Possible Risk Factors on Disease-Free Survival in CRC Patients
| Factors | DFS(Weeks±SD) | df | P value |
|---|---|---|---|
| Sex | 1 | 0.395 | |
| Male | (86.14±10.864) | ||
| Female | (70.67±11.368) | ||
| Age | 1 | <0.001** | |
| <60 | (61.69±7.547) | ||
| ≥60 | (108.21±15.605) | ||
| Tumor location | 1 | 0.004* | |
| Colon | (64.07±8.409) | ||
| Rectum | (102.50±14.476) | ||
| TNM stages | 1 | 0.001** | |
| Stage I-II | (96.15±13.295) | ||
| Stage III-IV | (64.02±8.338) | ||
| MSI status | 1 | 0.829 | |
| MSS | (78.16±9.088) | ||
| MSI | (85.91±16.637) | ||
| F. nucleatum | 1 | 0.041* | |
| Negative | (87.77±10.466) | ||
| Positive | (67.19±11.940) | ||
| HER-2 | 1 | 0.091 | |
| Negative | (70.47±10.831) | ||
| Positive | (87.91±16.637) | ||
| CD31 | 1 | 0.297 | |
| Negative | (70.52±13.744) | ||
| Positive | (83.18±9.599) | ||
| D2-40 | 1 | 0.297 | |
| Negative | (70.52±13.744) | ||
| Positive | (83.18±9.599) | ||
| CgA | 1 | 0.371 | |
| Negative | (81.21±8.325) | ||
| Positive | (56.20±14.263) | ||
| Syn | 1 | 0.724 | |
| Negative | (78.8±8.693) | ||
| Positive | (85.56±20.106) |
Note: *p <0.05 and **p<0.01 were considered to be statistically significant.
Abbreviations: DFS, disease-free survival; df, degree of freedom; CRC, colorectal cancer; F. nucleatum, Fusobacterium nucleatum; HER-2, human epidermal growth factor receptor-2; MSI, microsatellite instability; MSS, microsatellite stability; Syn, synaptophysin; CgA, chromogranin A.