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. 2022 Oct 3;18(15):5963–5977. doi: 10.7150/ijbs.72982

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The overexpression of NTF3 inhibited tumor growth in vivo and inhibited EMT transformation. A HCCLM3 overexpressing NTF3 (n=6) and the control group (n= 6) were implanted into nude mice for subcutaneous tumor imaging. B The growth curve of nude mice in the NTF3 group and control group. C, D The NTF3 group and control group tumor growth curve and tumor weight. E The representative images of hematoxylin-eosin (HE) staining and Ki67 immunostaining tumor tissues. F NTF3, E-cadherin (E-ca), N-cadherin (N-ca), and MMP9 immunohistochemical imaging of nude mouse tumor. G Tunel imaging of nude mouse tumor. H Representative image of HE staining and luciferase images of lung metastatic tumor. *P < 0.05; **P < 0.01; ***P < 0.001.