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. 2022 Oct 3;18(15):5963–5977. doi: 10.7150/ijbs.72982

Figure 5.

Figure 5

NTF3 acted as a ligand and bound to the receptor p75NTR to promote cell apoptosis. A qRT-PCR verified the expression of TrkA/B/C mRNA and p75NTR mRNA in QSG7701, L02, and 9 HCC cell lines. B WB verified the expression of p75NTR in QSG7701, L02, and 9 HCC cell lines. C, D Endogenous co-IP of Huh-7 and HCCLM3 revealed that NTF3 interacts with p75NTR. E The NTF3 and the control group of HCCLM3 and Huh-7 apoptosis-related protein levels changed. F NTF3 and the control group of HCCLM3 and Huh-7 were used to detect changes in the total phosphorylated JNK and P38 levels. *P < 0.05; **P < 0.01; ***P < 0.001.