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. 2022 Sep 1;18(15):5641–5652. doi: 10.7150/ijbs.76699

Table 6.

Cumulative negative conversion rates of SARS-CoV-2 RNA in the subgroups of interval time during treatment.

During treatment Interval time ≤4 days Interval time >4days
Control group (n=276) Treatment group (n=320) P value Control group (n=63) Treatment group (n=94) P value
Cumulative negative conversion rate, No./Total (%)
At Day2 20/276(7.25) 27/320(8.44) 0.59 13/63(20.63) 26/94(27.66) 0.32
At Day3 38/276(13.77) 75/320(23.44) 0.03* 22/63(34.92) 54/94(57.45) 0.006**
At Day4 88/276(31.88) 143/320(44.69) 0.01** 40/63(63.49) 70/94(74.47) 0.14
At Day5 163/276(59.06) 192/320(60.00) 0.82 50/63(79.37) 79/94(84.04) 0.45
At Day6 191/276(69.20) 238/320(74.38) 0.16 53/63(84.13) 84/94(89.36) 0.34
At Day7 229/276(82.97) 274/320(85.63) 0.37 57/63(90.48) 90/94(95.74) 0.20

Note: The interval time is the time between the onset of illness and randomization. Patients in every group were classified into subgroups according to interval time. The cumulative negative conversion rates were analyzed in the subgroup of interval time≤4 days and the subgroup of interval time>4 days. Among 858 patients, 753 patients who can provide the interval time from onset of illness to randomization were classified into subgroups according to interval time. *, P ≤0.05; **, P ≤0.01.