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. 2022 Sep 11;18(15):5724–5739. doi: 10.7150/ijbs.76140

Figure 1.

Figure 1

HDAC5 is overexpressed in mice and human HS. (A, B) The mRNA and protein levels of HDAC5 in normal mouse skin and HS tissues. (C) Images and quantitative analysis of immunohistochemical staining of HDAC5 in normal skin and HS tissues of mice. (Scale bar = 200 µm). (D) Immunofluorescence colocalization assay of HDAC5 and α-SMA in normal skin and HS tissues of mice. HDAC5 is labeled in red, and α-SMA is labeled in green. (Scale bar = 200 µm). (E, F) The mRNA and protein levels of HDAC5 in normal human skin and HS tissues. (G) Images and quantitative analysis of immunohistochemical staining of HDAC5 in normal skin and HS tissues of humans. (Scale bar = 200 µm). (H) Immunofluorescence colocalization assay of HDAC5 and α-SMA in normal skin and HS tissues of humans. HDAC5 is labeled in red, and α-SMA is labeled in green (Scale bar = 200 µm). Data are presented as the mean ± SD (n = 9 biologically independent animals and n = 20 biologically independent humans). ***P < 0.001.