Table 2.

A list of miRNA molecules regulating Fus1/Tusc2 levels in various cancers.

Name	UTR on mRNA	Expression, tissue	Reference
miR-93 miR-98	3’	Expressed at higher levels in SCLC lines compared to NSCLC lines and immortalized human bronchial epithelial cells (HBECs); miR-93 binds to TUSC2P mRNA (see below)	[55, 61]
miR-663	3’	Ovarian cancer	[56]
miR-197	3’	Expressed at higher levels in both SCLC and NSCLC compared to HBECs	[55]
miR-19a	3’	Lung cancer	[57]
miR-378	3’	Mesenchymal stem cells	[58]
miR-584	3’	Thyroid cancer	[59]
miR-138	5’	Triple-negative breast cancer	[60]
miR-17 miR-93 miR-299-3p miR-520a miR-608 miR-661	3’	Binds to TUSC2P mRNA expressed at high levels in normal cells (human white blood cells, human keratinocyte cell line HaCaT, and human bronchial epithelial cell line BEAS-2B). TUSC2P mRNA expressed at low levels in human breast cancer cell lines (MDA-MB231, MB468 and MT-1), a human glioblastoma cell line U87, and a mouse breast cancer cell line 4T1	[61]