Figure 3.

IDentif.AI drug interaction analysis. The IDentif.AI analysis identified two 2-drug combinations that may have unique interactions. (A) LVX/MEM surface indicated that highest %Inhibition may be achieved when both drugs are at L2, suggesting a synergistic interaction. (B) However, LVX/RFB surface suggested that the interaction is mildly synergistic and is mostly driven by LVX. L0, L1, and L2 correspond to the OACD concentration levels: level 0, level 1, and level 2. LVX: levofloxacin, MEM: meropenem, and RFB: rifabutin.