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SUPR effects induced by NIR-PIT. (A) Following injection, TSPCs are delivered through the vasculature and then bind to the tumor sites. (B) Tumor necrosis following NIR irradiation. (C) Super enhanced delivery of TSPCs into the treated tumor bed after the first NIR-PIT. (D) Repeated NIR irradiation enhances the therapeutic effect of NIR-PIT. SUPR: super enhanced permeability and retention.
