Table 2.
Correlations between CSF GAP-43 and other biomarkers.
| Baseline biomarkers | Baseline CSF GAP-43 | ||
|---|---|---|---|
| β coefficient | P value | R2 | |
| CSF Aβ42 | 0.01 | 0.819 | 0.088 |
| CSF p-tau | 0.745 | < 0.001 | 0.523 |
| CSF t-tau | 0.745 | < 0.001 | 0.550 |
| Plasma Aβ42/40 | − 0.077 | 0.273 | 0.035 |
| Plasma p-tau | 0.086 | 0.015 | 0.068 |
| Plasma NfL | 0.04 | 0.355 | 0.063 |
Baseline levels of all biomarkers were standardized to z scores so that the effects could be directly compared. Data are β coefficients (with P values) from linear regression models which were used to test associations between CSF GAP-43 and other biomarkers, adjusted for age, sex, education level, and APOE ε4 genotype.
CSF, cerebrospinal fluid; p-tau, phosphorylated tau 181; t-tau, total tau; NfL, neurofilament light.