Fig. 6. Structure of AspN-digested product of the LanII BGC.

Schematic diagram representing the ring pattern of the LanII product as determined by NMR, GC-MS, and HR-ESI MS/MS analysis. The black double-headed arrows and the red single-headed arrows represent characteristic NOESY and HMBC correlations across the thioether bridges, respectively. The numbers +5, +10, +15 and +20 represent amino acid positions in the core peptide beginning from the N-terminus. Modified amino acid residues are highlighted in red.