Table 3.
Characteristics of patients with postresuscitation shock (PRS) in the groups with favourable vs. unfavourable outcomea
| Characteristics | Favourablea outcome (N = 24) |
Unfavourablea outcome (N = 315) |
P value |
|---|---|---|---|
| Age, years, median [IQR] | 62.5 [57.1–69.8] | 67.6 [58.0–77.2] | 0.085 |
| Males, n (%) | 19 (79.2) | 191 (60.6) | 0.072 |
| Cardiac arrest location, n (%) | 0.012 | ||
| Home | 6 (25.0) | 163 (51.7) | |
| Elsewhere | 18 (75.0) | 152 (48.3) | |
| No-flow time, min, median [IQR] | 0.0 [0.0–2.0] | 2.0 [0.0–5.0] | 0.012 |
| Low-flow time, min, median [IQR] | 10.0 [5.0–12.5] | 20.0 [12.0–29.0] | < 0.0001 |
| Arterial pH, median [IQR] | 7.2 [7.0–7.3] | 7.2 [7.1–7.3] | 0.79 |
| PCI, n (%) | 1 (4.2) | 25(7.9) | 1.00 |
| Total epinephrine dose, mg, n (%) | 0.021 | ||
| 0 | 4 (17.4) | 11 (3.5) | |
| 1 or 2 | 8 (34.8) | 104 (33.3) | |
| ≥ 3 | 11 (47.8) | 197 (63.1) | |
| CAHP score, median [IQR] | 171 [150–185] | 196 [175–219] | 0.0001 |
| 33° groupb, n (%) | 14 (58.3) | 145 (46.0) | 0.24 |
| GCS score, median [IQR] | 3 [3–3] | 3 [3–3] | 0.58 |
PCI: percutaneous coronary intervention; CAHP: Cardiac Arrest Hospital Prognosis; GCS: Glasgow Coma Scale
aFavourable outcome was defined as a Cerebral Performance Category score of 1 or 2 on day 90 and unfavourable outcome as a Cerebral Performance Category score of 3, 4, or 5 on day 90
bIn the HYPERION trial used as the source of data for the present study, patients were allocated at random to treatment with hypothermia at 33 °C or normothermia at 37 °C