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Changes in cholesterol levels.
Percent fold-change (90% CI) from baseline to Day 84 in (A) LDL-C, (B) HDL-C, and (C) total-C following once daily administration of placebo or tropifexor at doses 30, 60, 90, and 150 μg. ∗p <0.05, ∗∗p <0.01, and ∗∗∗p <0.001 compared with placebo. HDL-C, HDL cholesterol; LDL-C, LDL cholesterol; total-C, total cholesterol.
