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. 2022 Oct 17;10(10):e6473. doi: 10.1002/ccr3.6473

TABLE 3.

Comparison of the cases of new‐onset acute type 1 diabetes after COVID‐19 vaccination

Authors Sasaki et al. Yano et al. Present case
Age and sex 73 years, male 51 years, female 59 years, male
Period from vaccination to onset 8 weeks 6 weeks 15 weeks
Onset patterns of type 1 diabetes Acute‐onset Acute‐onset Fulminant
HbA1c on admission 9.3% 10.3% 7.8%
Islet autoantibodies

GAD b Ab a (+)

IA‐2 Ab (−) d

IAA (+) e

GAD Ab (−)

IA‐2 Ab (−)

IAA (+)

GAD Ab (+)

IA‐2 Ab (−)

IAA (−)

Thyroid autoantibodies

TgAb (−) f

TPOAb (−) g

TRAb (−) h

TgAb (+)

TPOAb (+)

TgAb (−)

TPOAb (−)

TRAb (−)

ClassII

HLA c genotype

DRB1*04:05/04:05

DQB1*04:01/04:01

DRB1*09:01/09:01

DQB1*03:03/03:03

DRB1*04:05/09:01

DQB1*03:03/04:01

a

Ab, antibody.

b

GAD, glutamic acid decarboxylase.

c

HLA, human leukocyte antigen.

d

IA‐2, insulinoma‐associated protein‐2.

e

IAA, insulin antibody.

f

Tg, thyroglobulin.

g

TPO, thyroid peroxidase.

h

TR, thyrotropin receptor.