Table 2.
Therapeutic outcome in the study population*.
| Outcome |
Group A (n = 100) |
Group B (n = 100) |
P value |
|---|---|---|---|
| Endometrial thickness on hCGy trigger day (cm) | 1.02 ± 0.18 | 1.02 ± 0.20 | 0.445 |
| Duration of gonadotropin (Gonal-f) treatment (d) | 9.50 ± 2.44 | 9.90 ± 2.27 | 0.893 |
| Total doses of Gonal-f (IU) | 2385.50 ± 879.19 | 2527.63 ± 1170.33 | 0.047 |
| No. of collected oocytes | 6.63 ± 3.55 | 7.14 ± 3.43 | 0.604 |
| Fertilization rate (%) | 566/663 (85.4) | 598/714 (83.8) | 0.413 |
| No. of embryos transferred | 1.66 ± 0.48 | 1.64 ± 0.48 | 0.556 |
| Single embryo transfery (%) | 31 (32.6) | 36 (37.9) | 0.544 |
| Double embryos transfery (%) | 64 (67.4) | 59 (62.1) | 0.544 |
| No. of high-quality blastocysts? | 1.82 ± 2.12 | 1.43 ± 1.58 | 0.014 |
| Biochemical pregnancy rate (%)§ | 59 (59) | 49 (23) | 0.202 |
| Clinical pregnancy rate (%)|| | 51 (24) | 43 (25) | 0.321 |
| Implantation rate (%)z | 62/164 (37.8) | 51/161 (31.7) | 0.294 |
| Multiple pregnancy rate (%)¶ | 13/51 (25.5) | 9/43 (20.9) | 0.634 |
| Pregnancy loss rate (%) | 8 (15.7) | 8 (18.6) | 0.786 |
| Ectopic pregnancy rate (%) | 2 (3.9) | 1 (2.3) | 1.000 |
| Ongoing pregnancy rate (%)** | 41 (41.0) | 34 (34.0) | 0.381 |
Plus-minus values are indicated by means ± SD.
hCG, human chorionic gonadotropin.
yDenominator defined as number of transplants in each group.
The number of high-quality embryos was calculated as the total number of excellent embryos per group and the number of excellent embryos per capita per group. Defined as Gardner score 4BC or higher.
Biochemical pregnancy, i.e., serum β-hCG level ≥10 mIU/ml.
Clinical pregnancy referred to observations about the gestational sac using ultrasonography.
Embryo implantation rate was measured as number of observed intrauterine gestational sacs divided by the number of transferred embryos.
Multiple pregnancy rate was calculated as number of multiple pregnancy divided by the number of clinical pregnancy. All the multiple pregnancies are twins.
Ongoing pregnancy suggested the fetal heartbeat detected using ultrasonography until the 12th week of gestation.
Data are number/total number or number (%) unless stated otherwise.