Trained on A |
|
Trained on B |
|
A |
B |
C |
D |
|
|
A |
B |
C |
D |
A |
1 |
0.532 |
0.900 |
0.001 |
|
A |
1 |
0.001 |
0.002 |
0.001 |
B |
0.532 |
1 |
0.199 |
0.001 |
|
B |
0.001 |
1 |
0.900 |
0.001 |
C |
0.900 |
0.199 |
1 |
0.001 |
|
C |
0.002 |
0.900 |
1 |
0.001 |
D |
0.001 |
0.001 |
0.001 |
1 |
|
D |
0.001 |
0.001 |
0.001 |
1 |
Trained on C |
|
Trained on D |
|
A |
B |
C |
D |
|
|
A |
B |
C |
D |
A |
1 |
0.001 |
0.001 |
0.001 |
|
A |
1 |
0.001 |
0.001 |
0.001 |
B |
0.001 |
1 |
0.297 |
0.001 |
|
B |
0.001 |
1 |
0.732 |
0.340 |
C |
0.001 |
0.297 |
1 |
0.001 |
|
C |
0.001 |
0.732 |
1 |
0.039 |
D |
0.001 |
0.001 |
0.001 |
1 |
|
D |
0.001 |
0.340 |
0.039 |
1 |
|
|
|
(a) Single scanner training |
|
|
|
|
|
|
Trained on combined set (A, B, C, D) |
|
|
|
|
|
|
|
A |
B |
C |
D |
|
|
|
|
|
|
A |
1 |
0.002 |
0.046 |
0.001 |
|
|
|
|
|
|
B |
0.002 |
1 |
0.001 |
0.001 |
|
|
|
|
|
|
C |
0.046 |
0.001 |
1 |
0.013 |
|
|
|
|
|
|
D |
0.001 |
0.001 |
0.013 |
1 |
|
|
|
|
|
|
(b) All scanners training |
|
|
|
Trained and normalized on A |
|
Trained and normalized on B |
|
A |
B |
C |
D |
|
|
A |
B |
C |
D |
A |
1 |
0.311 |
0.270 |
0.257 |
|
A |
1 |
0.001 |
0.057 |
0.244 |
B |
0.311 |
1 |
0.900 |
0.900 |
|
B |
0.001 |
1 |
0.609 |
0.244 |
C |
0.270 |
0.900 |
1 |
0.900 |
|
C |
0.057 |
0.609 |
1 |
0.900 |
D |
0.257 |
0.900 |
0.900 |
1 |
|
D |
0.244 |
0.244 |
0.900 |
1 |
Trained and normalized on C |
|
Trained and normalized on D |
|
A |
B |
C |
D |
|
|
A |
B |
C |
D |
A |
1 |
0.001 |
0.001 |
0.008 |
|
A |
1 |
0.001 |
0.001 |
0.001 |
B |
0.001 |
1 |
0.037 |
0.001 |
|
B |
0.001 |
1 |
0.900 |
0.111 |
C |
0.001 |
0.037 |
1 |
0.025 |
|
C |
0.001 |
0.900 |
1 |
0.244 |
D |
0.008 |
0.001 |
0.025 |
1 |
|
D |
0.001 |
0.111 |
0.244 |
1 |
|
|
|
(c) Inter-scanner normalization |
|
|
|
Trained on A and fine-tuned for each scanner |
|
Trained on B and fine-tuned for each scanner |
|
A |
B |
C |
D |
|
|
A |
B |
C |
D |
A |
1 |
0.900 |
0.007 |
0.468 |
|
A |
1 |
0.900 |
0.001 |
0.900 |
B |
0.900 |
1 |
0.053 |
0.150 |
|
B |
0.900 |
1 |
0.001 |
0.900 |
C |
0.007 |
0.053 |
1 |
0.001 |
|
C |
0.001 |
0.001 |
1 |
0.001 |
D |
0.468 |
0.150 |
0.001 |
1 |
|
D |
0.900 |
0.900 |
0.001 |
1 |
Trained on C and fine-tuned for each scanner |
|
Trained on D and fine-tuned for each scanner |
|
A |
B |
C |
D |
|
|
A |
B |
C |
D |
A |
1 |
0.001 |
0.001 |
0.900 |
|
A |
1 |
0.283 |
0.900 |
0.001 |
B |
0.001 |
1 |
0.066 |
0.001 |
|
B |
0.283 |
1 |
0.593 |
0.066 |
C |
0.001 |
0.066 |
1 |
0.001 |
|
C |
0.900 |
0.593 |
1 |
0.001 |
D |
0.900 |
0.001 |
0.001 |
1 |
|
D |
0.001 |
0.066 |
0.001 |
1 |
|
|
|
(d) Inter-scanner fine-tuning |
|
|
|
HAC without normalization |
|
HAC normalized to scanner A |
|
A |
B |
C |
D |
|
|
A |
B |
C |
D |
A |
1 |
0.563 |
0.002 |
0.233 |
|
A |
1 |
0.092 |
0.001 |
0.870 |
B |
0.563 |
1 |
0.001 |
0.900 |
|
B |
0.092 |
1 |
0.001 |
0.386 |
C |
0.002 |
0.001 |
1 |
0.001 |
|
C |
0.001 |
0.001 |
1 |
0.001 |
D |
0.233 |
0.900 |
0.001 |
1 |
|
D |
0.870 |
0.386 |
0.001 |
1 |
HCT without normalization |
|
HCT with normalization to B |
|
A |
B |
C |
D |
|
|
A |
B |
C |
D |
A |
1 |
0.001 |
0.578 |
0.013 |
|
A |
1 |
0.001 |
0.402 |
0.419 |
B |
0.001 |
1 |
0.001 |
0.043 |
|
B |
0.001 |
1 |
0.001 |
0.001 |
C |
0.578 |
0.001 |
1 |
0.283 |
|
C |
0.402 |
0.001 |
1 |
0.900 |
D |
0.013 |
0.043 |
0.283 |
1 |
|
D |
0.419 |
0.001 |
0.900 |
1 |
|
|
|
(e) HCT and HAC methods |
|
|
|