Table 1.
Diagnostic results from Pathologists A, B, and C. We defined diagnostic concordance as instances where Pathologist C agreed with either Pathologists A and B on EPE and margin status and Gleason grade, for specimens with more than 5% tumor content.
| Slide ID | Margins assessment |
EPE assessment |
Tumor volume |
Gleason grade |
Highest resolution image reviewed |
Diagnostic concordance |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Path. A | Path. B | Path. C (Path. A VRI’s) | Path. C (Union VRI’s) | Path. A | Path. B | Path. C (Path. A VRI’s) | Path. C (Union VRI’s) | Path. A | Path. B | Path. A | Path. B | Path. C (Path. A VRI’s) | Path. C (Union VRI’s) | Path. C | Path. C | |
| 0 | Positive | Positive | Negative | Negative | Negative | Negative | Negative | Negative | 50% | 40% | 4+3 | 4+3 | 3+4 | Pathologist A VRI | No | |
| 1 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 40% | 30% | 3+4 | 3+4 | 3+4 | 3+4 | Union VRI | Yes |
| 2 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 25% | 30% | 3+4 | 3+4 | 3+4 | Pathologist A VRI | Yes | |
| 3 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 5% | 5% | 3+3 | 3+3 | 3+3 | Pathologist A VRI | Yes | |
| 4 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 1% | <5% | 3+3 | 3+3 | 3+3 | Pathologist A VRI | Yes | |
| 5 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 0% | 0% | Pathologist A VRI | Yes | ||||
| 6 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 0% | 0% | Union VRI | Yes | ||||
| 7 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 1% | <5% | 3+4 | 3+3 | 3+4 | Union VRI | Yes | |
| 8 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 0% | <5% | 3+3 | Pathologist A VRI | Yes | |||
| 9 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 0% | <5% | 3+3 | Pathologist A VRI | Yes | |||
| 10 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 0% | 0% | Pathologist A VRI | Yes | ||||
| 11 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 0% | 5% | 3+3 | Pathologist A VRI | Yes | |||
| 12 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 8% | 10% | 4+3 | 4+3 | 4+3 | Pathologist A VRI | Yes | |
| 13 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 1% | 0% | 3+4 | 3+3 | Pathologist A VRI | Yes | ||
| 14 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 0% | 0% | Pathologist A VRI | Yes | ||||
| 15 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 0% | 0% | Pathologist A VRI | Yes | ||||
| 16 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 0% | 0% | Pathologist A VRI | Yes | ||||
| 17 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 0% | 0% | Pathologist A VRI | Yes | ||||
| 18 | Negative | Negative | Negative | Negative | Negative | Positive | Negative | Negative | 60% | 60% | 3+4 | 3+4 | 3+4 | Pathologist A VRI | Yes | |
| 19 | Negative | Negative | Negative | Negative | Negative | Positive | Negative | Negative | 50% | 50% | 3+4 | 3+4 | 3+4 | Pathologist A VRI | Yes | |
| 20 | Negative | Negative | Negative | Negative | Negative | Positive | Negative | 10% | 25% | 3+3 | 3+3 | 3+3 | Union VRI | Yes | ||
| 21 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 1% | 5% | 3+3 | 3+4 | 3+3 | Pathologist A VRI | Yes | |
| 22 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 8% | 10% | 4+3 | 4+3 | 3+4 | Pathologist A VRI | Yes | |
| 23 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 25% | 25% | 4+3 | 3+4 | 4+3 | Pathologist A VRI | Yes | |
| 24 | Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative | 0% | 0% | Pathologist A VRI | Yes | ||||