Table 2.
Pathogens detected by mNGS.
| Sample type | Genus | Species | Number of reads | RPMd | Relative abundance (%) |
|---|---|---|---|---|---|
| CSFa | Leptospira | Leptospira interrogans | 4 | 0.3 | 0.07 |
| Urine | Leptospira | Leptospira interrogans | 9 | 0.74 | 0.06 |
| Sputum | Mycobacterium | MTBCb | 4 | 0.26 | < 0.01 |
| Plasmac | Leptospira | Leptospira interrogans | 2 | 0.06 | 4.65 |
aCSF, cerebrospinal fluid. bMTBC, Mycobacterium tuberculosis complex (the mNGS pipeline reports the species group (i.e., MTBC) rather than the detailed species due to their high homology). cCell-free DNA was used for metagenomic next-generation sequencing. dRPM, reads per million mapped reads.