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. 2022 Oct 4;14:1020092. doi: 10.3389/fnagi.2022.1020092

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Copyright © 2022 Alvarez, Trent, Goncalves, Pereira, Puri, Frazier, Sodhi and Pillai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic representation showing the neuronal infection of SARS-CoV-2 virus and CNS damage caused by the infection that leads to cognitive dysfunction and neurodegenerative diseases. Angiotensin-converting enzyme-2 (ACE-2), Alzheimer’s disease (AD), Parkinson’s disease (PD), Multiple sclerosis (MS), Amyotrophic lateral sclerosis (ALS), Multiple system atrophy (MSA), Ischemia stroke (IS).