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. 2022 Oct 4;13:991554. doi: 10.3389/fphar.2022.991554

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Copyright © 2022 Doroshenko, Tomkova, Kozar and Stroffekova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of Hyp or Goss on U87 MG cells viability and Bcl2 and Mcl1 protein levels. (A) Cell viability in the presence of Hyp and (B) Goss for 24 and 48 h. (C) The optical density band histograms of Bcl2 and Mcl1 normalized against GAPDH after 48 h incubation with Hyp or Goss. The histograms represent average of three independent experiments and the error bars represent the standard deviations from the average values. All experiments were repeated in triplicates. (D) Expression of Mcl1 and Bcl2 proteins in U87 MG whole cell lysates after 48 h incubation with Hyp or Goss was examined by western blot analysis. GAPDH was used as a housing protein.