Table 2.

Univariable and multivariable Cox regression analysis of prognostic parameters.

	p-value	Univariale HR (95% CI)	p-value	Multivariale HR (95% CI)
Age (> 70 years vs. ≤ 70 years)	0.012	1.810 (1.142 - 2.870)	0.001	2.513 (1.457 - 4.334)
Sex (male vs. female)	0.292	0.784 (0.499 - 1.232)
Other metastasis (with vs. without)	0.415	1.266 (0.718 - 2.233)
Chemo before diagnosis (yes vs. no)	0.293	1.356 (0.769 - 2.392)
Patient cluster (C4 vs. C3 vs. C1+C2)	0.001	1.699 (1.234 - 2.339)	0.003	1.648 (1.180 - 2.301)
PD-L1 (high vs. low)	0.006	2.214 (1.254 - 3.912)	0.001	3.316 (1.661 - 6.617)

HR, hazard ratio.