Table 2.
Results in the whole cohort according to surgical treatment received over time, all ages
| Surgical treatment group | Time interval | ||||
|---|---|---|---|---|---|
| 2003–2007 | 2008–2012 | P versus 2003–2007 | 2013–2016 | P versus 2003–2007 | |
| Elective resection | |||||
| 90-day mortality | 36 (4.4) | 19 (1.9) | – | 11 (1.5) | <0.001 |
| *2-year survival | 685 (84.2) | 883 (88.6) | – | 664 (91.7) | <0.001 |
| Emergency resection | |||||
| 90-day mortality | 44 (18.9) | 34 (17.2) | – | 18 (14.4) | – |
| 2-year survival | 118 (50.9) | 101 (51.0) | – | 70 (56.0) | – |
| All resections | |||||
| 90-day mortality | 80 (7.6) | 53 (4.4) | – | 29 (3.4) | <0.001 |
| 2-year survival | 803 (76.8) | 984 (82.3) | – | 734 (86.5) | <0.0001 |
| Non-resectional surgery | |||||
| 90-day mortality | 26 (28) | 17 (21.5) | – | 6 (9.4) | 0.005 |
| 2-year survival | 9 (9.7) | 14 (17.7) | – | 12 (18.8) | – |
| Local excision | |||||
| 90-day mortality | 0 (0) | 0 (0) | – | 0 (0) | – |
| 2-year survival | 38 (95) | 51 (91.1) | – | 75 (94.9) | – |
| No surgery | |||||
| 90-day mortality | 115 (36.3) | 126 (31.3) | – | 113 (28.5) | 0.026 |
| Median survival (95% c.i.) (months) | 5.3 (4.0–6.5) | 7.3 (5.9–8.6) | – | 8.0 (6.4–9.5) | <0.001 |
| 2-year survival | 26 (8.2) | 59 (14.7) | – | 84 (21.2) | <0.001 |
| All patients, all treatments | |||||
| 90-day mortality | 221 (14.8) | 196 (11.3) | – | 148 (10.7) | <0.001 |
| Median survival (95% c.i.) (years) | 3.4 (2.9–3.9) | 4.8 (4.0–5.6) | <0.0001 | 4.9 (4.0–5.7) | <0.001 |
| 2-year survival | 876 (58.6) | 1108 (64) | 0.002 | 905 (65.2) | <0.001 |
Values are n (%) unless otherwise indicated. *Survival presented as median (95 per cent c.i.) or as per cent survival at 2 years. Comparisons between groups assessed using log rank tests with significance set at less than 0.05 or chi-squared test as appropriate.