TABLE 2.
Baseline echocardiographic characteristics of the study population.
| All (n = 169) |
No clinical events (n = 125) |
Experienced clinical events (n = 44) |
P-value | |
| LVEDD, mm | 53.0 ± 6.1 | 52.0 ± 6.1 | 55.7 ± 5.1 | <0.001 |
| LVESD, mm | 36.6 ± 6.4 | 36.0 ± 6.4 | 38.3 ± 6.4 | 0.043 |
| LVEDV, ml | 156.4 (122.2-191.8) | 150.2 (118.6-179.8) | 171.5 (133.6-207.4) | 0.011 |
| LVESV, ml | 52.9 (41.1-71.1) | 52.3 (40.0-68.6) | 65.1 (44.4-84.1) | 0.112 |
| LVEF, % | 61.7 ± 9.1 | 61.7 ± 8.6 | 61.6 ± 10.6 | 0.940 |
| LV mass index, g/m2 | 101.3 (87.9-127.3) | 97.8 (81.9-119.7) | 110.1 (96.6-138.7) | 0.017 |
| LA volume index, ml/m2 | 57.0 (40.4-75.6) | 52.5 (39.1-67.7) | 75.9 (53.5-114.3) | <0.001 |
| LVGLS, % | -15.8 ± 5.4 | -15.7 ± 5.2 | -16.2 ± 6.1 | 0.597 |
| LA strain, % | 19.9 (11.7-30.0) | 24.0 (13.1-31.4) | 13.3 (9.3-23.8) | 0.003 |
| TLAEF, % | 35.0 (23.1-49.2) | 40.6 (24.2-50.4) | 26.7 (19.6-42.6) | 0.013 |
| MDPG, mmHg | 4.4 (3.3-6.0) | 4.0 (3.2-5.8) | 5.0 (3.7-6.9) | 0.031 |
| MR severity | <0.001 | |||
| Moderate, n (%) | 129 (76.3) | 107 (85.6) | 22 (50.0) | |
| Severe, n (%) | 40 (23.7) | 18 (14.4) | 22 (50.0) | |
| EROA, mm2 | 28.0 (23.0-34.5) | 27.0 (23.0-32.3) | 33.0 (27.0-45.8) | <0.001 |
| MR volume, ml | 36.7 (24.9-49.5) | 34.1 (25.0-45.6) | 51.7 (39.6-69.0) | <0.001 |
| MR fraction, % | 39.2 ± 12.2 | 36.5 ± 10.5 | 47.3 ± 13.7 | <0.001 |
| MR volume/LA strain, ml/% | 1.98 (1.11-3.28) | 1.57 (1.04-2.72) | 3.09 (2.06-5.80) | <0.001 |
| TR severity | <0.001 | |||
| Mild, n (%) | 54 (32.0) | 34 (27.2) | 20 (45.5) | |
| Moderate, n (%) | 19 (11.2) | 11 (8.8) | 8 (18.2) | |
| Severe, n (%) | 9 (5.4) | 3 (2.4) | 6 (13.7) | |
| PASP, mmHg | 30.2 (26.0-39.1) | 29.9 (25.0-35.0) | 37.5 (28.0-46.3) | <0.001 |
LVEDD, left ventricular end-diastolic dimension; LVESD, left ventricular end-systolic dimension; LVEDV, left ventricular end-diastolic volume; LVESV, left ventricular end-systolic volume; LVEF, left ventricular ejection fraction; LV, left ventricular; LA, left atrial; GLS, global longitudinal strain; TLAEF, total left atrial ejection fraction; MDPG, mean diastolic pressure gradient; MR, mitral regurgitation; EROA, effective regurgitant orifice area; TR, tricuspid regurgitation; PASP, pulmonary artery systolic pressure.