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. 2022 Sep;10(18):1014. doi: 10.21037/atm-22-4267

Figure 1.

Figure 1

Distribution of CD163+ TAMs in benign and malignant ovarian tumors and ascites. (A) The proportion of CD163+ TAMs in CD11b/CD68 double-positive mononuclear macrophages increased significantly in ascites of epithelial ovarian cancer patients. (B) In epithelial ovarian tissues, the proportion of CD163+ TAMs in CD11b/CD68 double-positive monocyte macrophages increased. (C) Compared with the peripheral blood of normal adult women and patients with benign ovarian cysts, the proportion of CD163+ TAMs in the peripheral blood of patients with epithelial ovarian cancer was higher in CD11b/CD68 double-positive mononuclear macrophages; meanwhile, in patients with ovarian cancer, the proportion of CD163+ TAMs in ascites was significantly higher than that in the peripheral blood of the same patient. The difference was statistically significant (n=40). ***, P<0.001. FSC, forward scatter; SSC, side scatter; TAMs, tumor-associated macrophages.